AMILOIDE A SERICO PDF

Dayer JM, Choy E. Therapeutic targets in rheumatoid arthritis: the interleukin-6 receptor. Rheumatology Oxford. Effects of interleukin-6 on the metabolism of connective tissue components in rheumatoid synovial fibroblasts. Arthritis Rheum.

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En LCR es posible detectar b-amiloide total b-amiloide y b-amiloide , el cual es similar en EA y controles. Se han descrito unas seis mutaciones aproximadamente. PS 2 Localizada en el cromosoma 1 y presente en formas familiares de inicio precoz. La presencia de 1 e4 triplica el riesgo de padecer la enfermedad, y cuando se es portador de 2 e4 el riesgo se incrementa hasta 9 veces. ApoE e4 es un factor de riesgo y no un gen causante porque no todos los portadores del alelo desarrollan el trastorno.

En algunos tipos de neuronas, los ONs se extienden hasta las dendritas proximales, mientras que en otros tipos permanece confinado al cuerpo celular. Mueren por apoptosis y necrosis. Por tanto apoptosis y necrosis deben solapar. A b induce apoptosis en neuronas en cultivo. En: Neuropathologia. Braak H, Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol ; Arch Neurobiol 6, , Acta Neuropathol, , Senile plaque like structures: Observation of a probably unknown type of senile plaque by periodic-acid methenamine silver PAM electron microscopy.

Diffuse type of senile plaques in the brains of Alzheimer-type dementia. Reexamination of the pathogenesis of the senile plaque. En: Zimmerman HM edit. Diffuse Lewy body disease: clinical features in 15 cases. J Neurol Neurosurg Psychiatry ; Science ; Mann DMA. Neurodegeneration ; 5: Neurology , Antigenic determinant properties of neurofibrillary tangles. Relevance to progressive supranuclear palsy. J Neural Transm SS, Antigenic determinants that distinguish cortical and subcortical neurofibrillary tangles.

Neurosci Lett , Acta Neuropathol ; Berl Ubiquitin in neurodegenerative diseases. Brain Pathol ; 3: Ubiquitin in cerebral amiloid angiopathy. J Neurological Sciences , Neuropil threads occur in dendrites of tangle-bearing nerve cells. Neuropathol Appl Neurobiol ; Senile plaque neurites fail to demonstrate anti-paired helical filaments and microtubule associated protein tau immunoreactive proteins in absence of neurofibrillary tangles of the cortex.

Constant neurofibrillary changes in the neocortex in progressive supranuclear palsy. Neurosci Lett ; J Neurosci ; Metabolic and degenerative diseases of the central nervous system.

Academic Press, Reexamination of granovacuolar degeneration. Hirano bodies observed in brain of the aged. Jpn J Geriatr ; Mech Aging Dev ; Modifications in the genetic expression in the aging brain. En: Wertheimer J, Marois M eds. Senile dementia: outlook for the future.

Liss New York, ; pp Neurol Sci ; Ann Neurol ; Biochem Soc Trans ; Hirano bodies accumulate c-terminal sequences of b-amyloid precursor protein b-APP epitopes. J Neuropathol Exp Neurol ; El tercer elemento de los centros nerviosos II. Bol de la Soc Esp de Biol ; 8: Murine brain macrophages induce NMDA receptor mediated neurotoxicity in vitro by secreting glutamate.

Nakajima M, Kohsaka S. Functional implications of microglia-derived secretory proteases. Topical Issues in microglial research. Singapore: Singapore Neuroscience Association. Moser M. Neurol ; Neurology ; American Psychiatric Association. Diagnostic and statistical manual of mental disorders. Rev Neurol ; 29 1 : Rev Neurol ; Part I. Part II. Khachaturian ZS. Arch Neurol 42 Braak Heiko and Braak Eva.

En: Koliatsos, Ratan. Cell death and diseases of the nervous system. Humana Press.

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